2012年6月10日星期日

Cinnamyl Alcohol for Flavor and Fragrance



Physicochemical property

Cinnamic Alcohol, Cinnamal Alcohol
CAS NO.: 104-54-1
Assay: 98%
Molecular Formula:C9H10O
Molecular Weight:134.18
Melting point: 33
Boiling point:256.6
EINECS NO.: 203-212-3
Packing: 200KG /drum
Appearance: White to light yellow crystal, or colorless to light yellow liquid

Application field and functions
Pharmaceutical Raw Materials, flavors and fragrances, food additives, flavor agent, cosmetics.
It is widely used in food and beverage processing, cosmetics, hygiene products and other industries. Among them, the food and beverage processing industry is a major consumer of flavors and fragrances field, accounting for47% of the total market demand. The fixative agent which is an integral part of the flavors and fragrances, also is known as Paul deodorant. Its role is to make a variety of spices in the flavor volatile uniform, and prevent rapid evaporation, so that the flavors and aroma of can keep long time The fixative agent may not change the flavor of the original flavor formula, and must be soluble in the other monomer spices.
Food flavoring: It can be redeployed daily flavor, food flavorings. It also can be used in beverage, cold drink, confections, wines as flavor agent.
Daily fragrances: flavor and fragrances for cosmetics soap and daily use.
Flavor fixative: high efficient, safe, green, available in food, beverage etc.
It helps deploying flavor and fragrance such as rose, fruit etc, which is milder, more durable and comfortable than that deployed from essence oil. 
Preservatives: to keep food/meat fresh
Pharmaceutical ingredients: It is an important ingredient in paclitaxel, a medicine for ovarian cancer and breast cancer etc.

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2012年6月7日星期四

octyl p-methoxycinnamate:The best plastic anti-aging agent





In daily life we often see plastic film aging in the sun exposure for a long time will occur after aging plastic color, thin, brittle or even disappear, etc. It is a manifestation of aging plastic. Plastic can be fragments or powder according to the degree of aging. If this type of plastic itself is non-toxic, so aging is harmless to human, such as some PVC products.


Some people have a test in Shandong, Hebei, Liaoning, Jilin, Heilongjiang and other areas of performance plastic windows, the main purpose is to observe the natural state of the aging of the plastic window color case. The survey showed that, the vast majority of plastic profiles for 3 years in age began, with up to 5 years of aging will be very serious. In order to prevent plastic from aging,people  added some of the antioxidantin, light stabilizer, heat stabilizer additives to plastics to delay or inhibit oxidation and degradation. Currently, the plastic anti-aging agent is used frequently lead salt products. However, these formulations used in the lead salts and sulfides produces a black lead sulfide material in the air easy to cause black spots on the surface profile, accelerate the aging of plastic, thus forming a cycle is difficult to reconcile the contradictions.

In order to overcome the traditional plastic shortcomings, a new plastic additive is developed. According to the scientific experiments,the plastic under natural conditions, using 5 years of aging will appear small. Octyl methoxycinnamate is a good absorber of ultraviolet UVB region, can effectively prevent the 280-330mm UV. Nowadays, the Octyl methoxy anti-aging agents for inks and UV absorbers is widely used.


Ferulic acid:To create the perfect new sport-drink


As we all know, regular exercise is good for our health. But scientists have discovered recently, movement also has certain side effects, namely, it has certain implicit damage to human body. The arch-criminal of this damage is free radicals.
   The scientists found further that free radicals ,which is damage to human health  are almost related with high active oxygen containing material, they called these free radicals” living oxygen free radicals”. Active oxygen free radical damage to human body is actually an oxidation process. Therefore, in order to reduce free radical damage, we should start from antioxidant.
   At present, the domestic market of specialized sports drink has two major brands: a Gatorade, another is a high-energy solid beverage. But these sports drinks only can supply physical fitness after exercise.
   Ferulic acid ( also known as the 3 - methoxy - 4 - hydroxy cinnamic acid ) is a kind of good and non-toxic plant-derived antioxidants, and can stimulate the secretion of the hormone, many foreign sports food are added with ferulic acid or ferulic acid herbs. 


 Research shows, ferulic acid has the good antioxidant activity, hydrogen peroxide, superoxide radical, peroxynitrite has strong scavenging effect. Ferulic acid can not only free radical quenching, regulating the body's physiological function, inhibit the generation of free radical enzyme, promote free radical scavenging enzymes produced, but also greatly increased glutathione S-transferase and quinone garden enzyme activity, inhibition of tyrosinase activity, and membrane phospholipids with amide conjugates, protect membrane lipid from free radical attack.

2012年6月5日星期二

2-Fluorine Cinnamic Acid : A Better New Medicine Ingredient


According to the census data makes clear, anorectal disease incidence rate of 59.1%, hemorrhoids, anorectal diseases accounted for all 87.25%, which again the hemorrhoids are the most common, accounting for 52.19% of all anorectal diseases. Men and women may get sick, female incidence rate was 67%, the incidence in males was 53.9%; any age can come on, 20-40, which is more common, and with the growth of age and gradually increase, it is an old saying " nine out of ten person has hemorrhoids ".

Treatment of hemorrhoids, the general idea is: medical treatment for the first, only when medical treatment is not good, hemorrhoids, anal prolapse with severe hematochezia from excessive,can has the operation treatment. In the choice of drugs, medication due to pass through the digestive tract, thelocation of disease, so the adverse reaction is relatively small, is the preferred treatment of hemorrhoids. At present, the market has a lot of kinds of hemorrhoids medication, for its effect or the use of methods, the used people probably have deep feelings.

Recently, people invented a 2 fluoride cinnamic acid as the main raw materials of hemorrhoids drugs for external use. The drug can be wiped, affixed to fumigation and washing, the effect is very good, the use of 2 - fluorine cinnamic acid is a kind of pharmaceutical intermediates, pharmaceutical raw materials, are often used to treat hemorrhoids toxic swelling, traumatic injury, traumatic swelling and pain.


2,4-Dichlorocinnamic Acid: The New Green Multifunctional Pesticide


China is one of the largest agricultural countries in the world, pesticide plays a decisive role in our country, so we have paid more attention in researching and developing the pesticide for decades. The new pesticides in our country, eventually, many of which are harmful to human beings. 

Recently, the farm in Xinjiang Heihe has researched and applicated of a novel multifunctional pesticides. The pesticide with 2, 4 - dichloro cinnamic acid to be main raw material, not only has long sterilization, insecticidal effect, but also has good permeability, easy absorption by plants, increase plant photosynthetic efficiency, increase cells vitality, promote plant growth and productivity function, good pesticide and plant growth regulators combined into one

The actual application of the farm in Xinjiang Heihe prevent that using new pesticides of 2, 4 - dichlorocinnamic acid on fruits and vegetables, has no harmful residues, it’s safety and green for the humans. What makes the user be overjoyed is that a new pesticide, can not only promote the maturation of fruits and vegetables, increase its yield, but also the long-term effective bactericidal action can continue to fruit and vegetable packaging and transportation process!

Fruit and vegetable picking can no longer take preservative measures!
Also, new pesticide less dosage, no toxic residue, no pollution, the cost is lower than traditional pesticide


2012年6月3日星期日

Good Effect of Cinnamaldehyde

Cinnamaldehyde and vanillin spice traditionally used as food, there is a better anti-mildew and antibacterial activity. Vanillin as a white or light yellow crystal, owing to its unique sweet vanilla aroma, used for making ice cream, chocolate class Western-style dim sum; while Cinnamaldehyde as a unique cinnamon scent with a yellow liquid, used for bread, meat, fish, vegetables , eggs, soups, cakes, desserts, sauces and seasoning compound.

According to the research, Cinnamaldehyde and vanillin, while having a good mildew and antibacterial, but individually as a preservative, the mold can play a role in concentration, has obvious smell, thus affecting the food value of the goods, including Cinnamaldehyde odor flavor more pronounced.

In order to overcome these shortcomings, researchers with a mixture of both active ingredients as a mold made of mildew, mixed-use, their respective effective concentration when used alone is only effective concentration of the respective mold 1/10-1/20 , and the smell disappeared, food appearance of browning did not occur. Mildew in cinnamaldehyde and vanillin in the weight ratio of 0.001-1, to 0.001-0.1 most appropriate. The preservative can be made that the ratio of vanillin and Cinnamaldehyde in alcohol solution, water - alcohol solution or propylene glycol solution can also be sprayed on the above-mentioned preparations alcohol solution of glucose, dextrin or large rice in the system through the dry into a powder application.

The use of vanillin and Cinnamaldehyde mixture made of antifungal agents, is absolutely safe to humans and animals can be widely used in food mold, especially for cakes, pastries, rice cakes, rice cakes, jams and other food for mildew. To use a wide variety, such as coating, powder scatter, spray on food surfaces, or to blend in the food raw materials, or to apply on food wrappers on both.


2012年6月1日星期五

Application of Cinnamic Aldeyde


Name: Cinnamic aldehyde
Synonyms: cinnamaldehydeβ-phenylacrolein , Trans-Cinnamaldehyde
Molecular formula: C9H8O
CAS: 104-55-2
Appearance: Colorless or light yellow liquid
Aroma Unique fragrances
Content (Weather chromatography analysis) 98%
 
As the constant development of scientific and technological level, the scope of application of cinnamaldehyde become more and more widely, applications continue to extend, in the flavors and fragrances, food additives, pharmaceutical chemicals and feed applications, and other aspects. This article focuses on cinnamic aldehyde in the pharmaceutical and chemical fields.

1. Cinnamaldehyde-- the Application in Medicine

1. Disinfection Antiseptic, especially for Fungi a significant effect.

Escherichia coli, Bacillus subtilis and Staphylococcus aureus bacteria, Staphylococcus albus, Shigella, typhoid and paratyphoid A bacillus, pneumococcus, Aerobacter aerogenes, Proteus, Bacillus anthracis, Salmonella enteritidis, Vibrio cholerae, etc. are inhibition. And against Gram-positive bacteria, a significant bactericidal effect can be used to treat a variety of diseases caused by bacterial infection. Minimum inhibitory concentration (MIC) for the 0.02-0.07ul/ml, right deep pathogenic fungi, MIC for 0.1-0.3ul/ml.

Japanese medical experts recently found cinnamaldehyde a significant effect on the fungi of 22 species of pathogenic fungi conditions Cinnamaldehyde studies have shown that anti-fungal effect: Cinnamic aldehyde is the active anti-fungal substances, mainly through the destruction of fungal cell walls, so that drug infiltration of fungal cells, destruction of organelles and play a bactericidal effect.

2. Antiulcer, strengthening the stomach, intestinal movement.

3. Fat Decomposition.

Cinnamic aldehyde can inhibit the epinephrine and ACTH right of free fatty acids to promote the synthesis of glucose and fat, cinnamic acid, also have such effect, but the role is far greater than cinnamaldehyde cinnamic acid. Thus, drugs can be used for blood glucose control, enhance the performance of glucose-insulin replacement, diabetes control.

4. Antiviral Activity of influenza virus, SV10 virus, a strong inhibitory effect caused by the tumor.

5. Anticancer effect. Inhibit tumors, and have the anti-mutagenic and anti-radiation effect.

6. Expansion of the role of blood vessels and blood pressure. Right adrenal hypertension have blood pressure lowering.

7. Aphrodisiac effect. Treatment Research Center, Chicago, a study showed that cinnamic aldehyde makes a certain effect aphrodisiac for men.

8. Commonly used in external medicine.

Applied in massage fluid, beauty products, promote blood circulation, which can improve water retention, scars on the skin, softening and remove fibroids.

In short, cinnamic aldehyde can be used not only to its own raw material medicine, but also to a variety of external agents, finished drugs, the process can be further in-depth synthesis of a number of powerful drug efficacy.

II. Cinnamaldehyde in the application of chemical

1. Organic chemical synthesis. For the synthesis of α-bromo cinnamic aldehyde, cinnamic acid, cinnamic alcohol, cinnamic nitrile and other products.

2. In the industry, can also be made of color reagent, laboratory reagent.

3. Insecticide, insect repellent, refrigerator deodorant, preservation agent.

Larvae of the Aedes mosquitoes spread yellow fever has a strong killing effect, it will become a new type of insecticide. Cinnamaldehyde is safe, environmentally and smell fragrant, which can be used directly drains (sewers) or vehicle-specific flavor, air fresheners, oxygen generator, refrigerator deodorant, preservation agent.

4. Cinnamic aldehyde can also be applied to oil exploration in the sterilization algicide, acidification inhibitor, to replace the current use of glutaraldehyde and other traditional antiseptic bactericide, which can significantly increase oil production and improve oil quality and reduce mining costs. At present, Hebei Oilfield, Shengli Oilfield have purchased Cinnamaldehyde from us. 

5. Cinnamaldehyde is widely used in anti-corrosion anti-mildew freshness.

6. Cinnamic aldehyde gum sterilization deodorant.
Liangbu Wu reported that the U.S. University of Illinois at Chicago College of Dentistry has an expert report the latest research results, contain cinnamaldehyde composition of natural plant extracts such as the taste of chewing gum can kill bacteria in the mouth , and thus reduce the production of bad breath.

III. The flavors and fragrances 

Modulation as cinnamic aldehyde not only can flavor a variety of flavors, but also on oral play the dual effect sterilization and deodorization. Commonly used in toothpaste, chewing gum, breath fresh oral care agent.

IV. Cinnamaldehyde application in the food industry

Cinnamic aldehyde in foods commonly used in the consumption of spices, fresh anti-corrosion mildew (paper), and a very good seasoning (material) oil, used to improve the taste flavor. Such as: instant noodles, chewing gum, betel nuts and other foodstuffs, as well as bread, cakes, pastries and other baked goods.

Cinnamic aldehyde can be used for anti-mold plastic wrap. Fruit, food preservation and packaging materials.


References:
"Information incense at home and abroad," "China's Pesticide Information Network"
"Komori Medicine Expo," the Oxford English Dictionary
"Baking Industry" Medicine Expo
"Natural Aromatherapy Wikipedia" Japan Medical Abstracts

"China Medical Encyclopedia," University of Chicago, 1997 Annual Report