Application of Cinnamic Aldeyde

Name: Cinnamic aldehyde

Synonyms: cinnamaldehyde，β-phenylacrolein , Trans-Cinnamaldehyde

Molecular formula: C9H8O

CAS: 104-55-2

Appearance: Colorless or light yellow liquid

Aroma Unique fragrances

Content (Weather chromatography analysis) ≥ 98%

 

As the constant development of scientific and technological level, the scope of application of cinnamaldehyde become more and more widely, applications continue to extend, in the flavors and fragrances, food additives, pharmaceutical chemicals and feed applications, and other aspects. This article focuses on cinnamic aldehyde in the pharmaceutical and chemical fields.

1. Cinnamaldehyde-- the Application in Medicine

1. Disinfection Antiseptic, especially for Fungi a significant effect.

Escherichia coli, Bacillus subtilis and Staphylococcus aureus bacteria, Staphylococcus albus, Shigella, typhoid and paratyphoid A bacillus, pneumococcus, Aerobacter aerogenes, Proteus, Bacillus anthracis, Salmonella enteritidis, Vibrio cholerae, etc. are inhibition. And against Gram-positive bacteria, a significant bactericidal effect can be used to treat a variety of diseases caused by bacterial infection. Minimum inhibitory concentration (MIC) for the 0.02-0.07ul/ml, right deep pathogenic fungi, MIC for 0.1-0.3ul/ml.

Japanese medical experts recently found cinnamaldehyde a significant effect on the fungi of 22 species of pathogenic fungi conditions Cinnamaldehyde studies have shown that anti-fungal effect: Cinnamic aldehyde is the active anti-fungal substances, mainly through the destruction of fungal cell walls, so that drug infiltration of fungal cells, destruction of organelles and play a bactericidal effect.

2. Antiulcer, strengthening the stomach, intestinal movement.

3. Fat Decomposition.

Cinnamic aldehyde can inhibit the epinephrine and ACTH right of free fatty acids to promote the synthesis of glucose and fat, cinnamic acid, also have such effect, but the role is far greater than cinnamaldehyde cinnamic acid. Thus, drugs can be used for blood glucose control, enhance the performance of glucose-insulin replacement, diabetes control.

4. Antiviral Activity of influenza virus, SV10 virus, a strong inhibitory effect caused by the tumor.

5. Anticancer effect. Inhibit tumors, and have the anti-mutagenic and anti-radiation effect.

6. Expansion of the role of blood vessels and blood pressure. Right adrenal hypertension have blood pressure lowering.

7. Aphrodisiac effect. Treatment Research Center, Chicago, a study showed that cinnamic aldehyde makes a certain effect aphrodisiac for men.

8. Commonly used in external medicine.

Applied in massage fluid, beauty products, promote blood circulation, which can improve water retention, scars on the skin, softening and remove fibroids.

In short, cinnamic aldehyde can be used not only to its own raw material medicine, but also to a variety of external agents, finished drugs, the process can be further in-depth synthesis of a number of powerful drug efficacy.

II. Cinnamaldehyde in the application of chemical

1. Organic chemical synthesis. For the synthesis of α-bromo cinnamic aldehyde, cinnamic acid, cinnamic alcohol, cinnamic nitrile and other products.

2. In the industry, can also be made of color reagent, laboratory reagent.

3. Insecticide, insect repellent, refrigerator deodorant, preservation agent.

Larvae of the Aedes mosquitoes spread yellow fever has a strong killing effect, it will become a new type of insecticide. Cinnamaldehyde is safe, environmentally and smell fragrant, which can be used directly drains (sewers) or vehicle-specific flavor, air fresheners, oxygen generator, refrigerator deodorant, preservation agent.

4. Cinnamic aldehyde can also be applied to oil exploration in the sterilization algicide, acidification inhibitor, to replace the current use of glutaraldehyde and other traditional antiseptic bactericide, which can significantly increase oil production and improve oil quality and reduce mining costs. At present, Hebei Oilfield, Shengli Oilfield have purchased Cinnamaldehyde from us. 

5. Cinnamaldehyde is widely used in anti-corrosion anti-mildew freshness.

6. Cinnamic aldehyde gum sterilization deodorant.
Liangbu Wu reported that the U.S. University of Illinois at Chicago College of Dentistry has an expert report the latest research results, contain cinnamaldehyde composition of natural plant extracts such as the taste of chewing gum can kill bacteria in the mouth , and thus reduce the production of bad breath.

III. The flavors and fragrances 

Modulation as cinnamic aldehyde not only can flavor a variety of flavors, but also on oral play the dual effect sterilization and deodorization. Commonly used in toothpaste, chewing gum, breath fresh oral care agent.

IV. Cinnamaldehyde application in the food industry

Cinnamic aldehyde in foods commonly used in the consumption of spices, fresh anti-corrosion mildew (paper), and a very good seasoning (material) oil, used to improve the taste flavor. Such as: instant noodles, chewing gum, betel nuts and other foodstuffs, as well as bread, cakes, pastries and other baked goods.

Cinnamic aldehyde can be used for anti-mold plastic wrap. Fruit, food preservation and packaging materials.

References:

"Information incense at home and abroad," "China's Pesticide Information Network"

"Komori Medicine Expo," the Oxford English Dictionary

"Baking Industry" Medicine Expo

"Natural Aromatherapy Wikipedia" Japan Medical Abstracts

"China Medical Encyclopedia," University of Chicago, 1997 Annual Report