Name: Cinnamic aldehyde
Synonyms: cinnamaldehyde，β-phenylacrolein
, Trans-Cinnamaldehyde
Molecular formula: C9H8O
CAS: 104-55-2
Appearance: Colorless or light yellow
liquid
Aroma Unique fragrances
Content (Weather chromatography analysis) ≥ 98%
As the constant development of scientific
and technological level, the scope of application of cinnamaldehyde become more
and more widely, applications continue to extend, in the flavors and
fragrances, food additives, pharmaceutical chemicals and feed applications, and
other aspects. This article focuses on cinnamic aldehyde in the pharmaceutical
and chemical fields.
1. Cinnamaldehyde-- the Application in Medicine
1. Disinfection Antiseptic, especially for Fungi
a significant effect.
Escherichia coli, Bacillus subtilis and
Staphylococcus aureus bacteria, Staphylococcus albus, Shigella, typhoid and
paratyphoid A bacillus, pneumococcus, Aerobacter aerogenes, Proteus, Bacillus
anthracis, Salmonella enteritidis, Vibrio cholerae, etc. are inhibition. And against
Gram-positive bacteria, a significant bactericidal effect can be used to treat
a variety of diseases caused by bacterial infection. Minimum inhibitory
concentration (MIC) for the 0.02-0.07ul/ml, right deep pathogenic fungi, MIC
for 0.1-0.3ul/ml.
Japanese medical experts recently found
cinnamaldehyde a significant effect on the fungi of 22 species of pathogenic
fungi conditions Cinnamaldehyde studies have shown that anti-fungal effect:
Cinnamic aldehyde is the active anti-fungal substances, mainly through the
destruction of fungal cell walls, so that drug infiltration of fungal cells,
destruction of organelles and play a bactericidal effect.
2. Antiulcer, strengthening the stomach,
intestinal movement.
3. Fat Decomposition.
Cinnamic aldehyde can inhibit the
epinephrine and ACTH right of free fatty acids to promote the synthesis of
glucose and fat, cinnamic acid, also have such effect, but the role is far
greater than cinnamaldehyde cinnamic acid. Thus, drugs can be used for blood
glucose control, enhance the performance of glucose-insulin replacement,
diabetes control.
4. Antiviral Activity of influenza virus,
SV10 virus, a strong inhibitory effect caused by the tumor.
5. Anticancer effect. Inhibit tumors, and
have the anti-mutagenic and anti-radiation effect.
6. Expansion of the role of blood vessels
and blood pressure. Right adrenal hypertension have blood pressure lowering.
7. Aphrodisiac effect. Treatment Research
Center, Chicago, a study showed that cinnamic
aldehyde makes a certain effect aphrodisiac for men.
8. Commonly used in external medicine.
Applied in massage fluid, beauty products, promote blood circulation, which can improve water retention, scars on the skin, softening and remove
fibroids.
In short, cinnamic aldehyde can be used not
only to its own raw material medicine, but also to a variety of external
agents, finished drugs, the process can be further in-depth synthesis of a
number of powerful drug efficacy.
II. Cinnamaldehyde in the application of
chemical
1. Organic chemical synthesis. For the
synthesis of α-bromo cinnamic aldehyde, cinnamic acid, cinnamic alcohol,
cinnamic nitrile and other products.
2. In the industry, can also be made of
color reagent, laboratory reagent.
3. Insecticide, insect repellent,
refrigerator deodorant, preservation agent.
Larvae of the Aedes mosquitoes spread
yellow fever has a strong killing effect, it will become a new type of
insecticide. Cinnamaldehyde is safe, environmentally and smell
fragrant, which can be used directly drains (sewers) or vehicle-specific flavor, air
fresheners, oxygen generator, refrigerator deodorant, preservation agent.
4. Cinnamic aldehyde can also be applied to
oil exploration in the sterilization algicide, acidification inhibitor, to
replace the current use of glutaraldehyde and other traditional antiseptic
bactericide, which can significantly increase oil production and improve oil quality
and reduce mining costs. At present, Hebei Oilfield, Shengli Oilfield
have purchased Cinnamaldehyde from us.
5. Cinnamaldehyde is widely
used in anti-corrosion anti-mildew freshness.
6. Cinnamic aldehyde gum sterilization
deodorant.
Liangbu Wu reported that the U.S. University of Illinois at Chicago
College of Dentistry has an expert report the latest research results, contain
cinnamaldehyde composition of natural plant extracts such as the taste of
chewing gum can kill bacteria in the mouth , and thus reduce the production of
bad breath.
III. The flavors and fragrances
Modulation as cinnamic aldehyde not only can
flavor a variety of flavors, but also on oral play the dual effect
sterilization and deodorization. Commonly used in toothpaste, chewing gum,
breath fresh oral care agent.
IV. Cinnamaldehyde application in the food
industry
Cinnamic aldehyde in foods commonly used in
the consumption of spices, fresh anti-corrosion mildew (paper), and a very
good seasoning (material) oil, used to improve the taste flavor. Such as: instant
noodles, chewing gum, betel nuts and other foodstuffs, as well as bread, cakes,
pastries and other baked goods.
Cinnamic aldehyde can be used for anti-mold
plastic wrap. Fruit, food preservation and packaging materials.
References:
"Information incense at home and
abroad," "China's
Pesticide Information Network"
"Komori Medicine Expo," the Oxford English Dictionary
"Baking Industry" Medicine Expo
"Natural Aromatherapy Wikipedia" Japan Medical
Abstracts
"China
Medical Encyclopedia," University
of Chicago, 1997 Annual
Report
